Thursday 28th of March 2024
 

Virtual Natural Product Library - full text searchable database


Subhash Chandra Bose. Kotte, Pavan Kumar K.V.T.S, Ravi Kumar Tumuluri, Shriram Raghavan, P.K. Dubey and P.M. Murali

Small molecules occurring in nature have special significance to mankind. They have varied applications from healthcare, food, nutrition, agriculture, personal care and well-being. These natural small molecules are from very diverse sources from the rarest plants to deep sea creatures. Recently they have assumed a lot of significance as pharmaceutical companies is constantly pushing the horizons to make them druggable due to their inherent bioactivities. Though they are not easy to synthesize or isolate, yet their diverse molecular scaffold confers them significance especially given the fact of prevailing resistance to drug scaffolds presently being used in the clinics. Hence its of paramount importance to have a database of diverse natural small molecules through the present effort of creating a Virtual Natural Products Library (VNPL-version 0.15).

Keywords: Database; Druggable; Natural Compounds

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ABOUT THE AUTHORS

Subhash Chandra Bose. Kotte
Subhash Chandra Bose. Kotte obtained his Masters in Chemistry from Jawaharlal Nehru Technological University at Hyderabad. He specializes in Chemical synthesis, Analytics and presently a researcher in the field of Analytical Chemistry with Jawaharlal Nehru Technological University Hyderabad.

Pavan Kumar K.V.T.S
K.V.T.S.Pavan Kumar obtained his Masters in biochemistry. He specializes in Bio-informatics and is presently a researcher in the field of Plant biotechnology with Dalmia Centre for Research and Development.

Ravi Kumar Tumuluri
T. Ravi Kumar obtained his Masters in biochemistry. He is presently a researcher in the field of biochemistry with Acharya Nagarjuna University

Shriram Raghavan
Shriram Raghavan obtained his Masters in biochemical engineering and biotechnology from HP University at Shimla. He specializes in Bio-informatics and is presently a researcher in this field with Dalmia Centre for Research and Development.

P.K. Dubey
Dr. P.K. Dubey is M.Sc.( OU), Ph.D (O.U), Specialized in Organic Chemistry. His research interests include Synthetic organic chemistry. He guided over 20 Ph.D. Students and presently guiding seven students for Ph.D. Degrees. He published over 150 research papers. He has 32 years of teaching and research experience.

P.M. Murali
Dr. P.M. Murali received a Ph.D. in Microbiology and Microbial technology from Madurai Kamaraj University, having over 22 years of experience in Pharmaceutical & Healthcare R&D, including management of more than 10 clinical trials, in particular in respiratory diseases. He has remained the Founder and Director of Dalmia Centre for Research and Development for 16 years, developing and launching natural product based therapeutics, and Founder and Chairman of MLC & Netpeople group of IT & Telecom companies (Networking solutions, Banking Security and communication services). Dr. Murali is a former Indo-US scientist at Battelle-Kettering, Ohio and fellow of Unilever India. Dr. Murali is the Managing Director and CEO of Evolva India since September 2006 and in addition presently he is President of the Association of Biotechnology Led enterprises (ABLE) in India.


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